Nur77 senses LPS and dsDNA for non-canonical inflammasome

nuri77Fure 1 Loss of Nur77 in BMDMs leads to enhanced efferocytosis due to an increased integrin β3 and β5 snaling.(A) In vitro uptake of fluorescently-labeled apoptoticThe nuclear receptor Nur77 (also known as TR3 or NGFI-B), encoded by the immediate early gene Nr4a1, belongs to the steroidthyroidretinoid superfamily (Hazel et al.,